Thursday April 8th

Welcome Remarks with Dr. Ana Andreazza, Scientific Director, MITO2i.

- Introduction: The MITO Voice -

Opening Remarks with Dr. Christine Allen, Associate Vice-President and Vice-Provost Strategic Initiatives University of Toronto.

Keynote Speaker: "Targeting the cellular metabolism to treat tissue-specific mitochondrial diseases”

 

Dr. Rita Horvath MD, PhD. Director of Research (Clinical) - Genetics of Rare Neurological Disorders Department of Clinical Neurosciences,

 

University of Cambridge, John Van Geest Cambridge Centre for Brain Repair

Break.

Introduction of Innovation Grant Awardees by Sonya Brijbassi, Associate Director Strategy & Partnerships MITO2i.

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Quick Fire Talks from the Innovation Grant Awardees:

Moderator: Dr. Ben Goldstein

 

Professor of Psychiatry and Pharmacology Director, Centre for Youth Bipolar Disorder, Centre for Addiction and Mental Health.

Dr. Robert Screaton, Senior Scientist Sunnybrook Research Institute

 

Mitochondrial Metabolism Vulnerabilities in Breast Cancer:

Dr. Ingrid Tein, Director, Neurometabolic Clinic, Hospital for Sick Children

Identification of candidate genetic susceptibility variants in the carnitine transporter and carnitine biosynthesis gene families in Autism Spectrum Disorder: A novel precision medicine target

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Dr. Walid Houry, Professor, Department of Biochemistry, University of Toronto

 

Investigation of the role of ClpP protease deficiency in Perrault syndrome with Leukodystrophy.

Dr. Laura Rosella, Associate Professor, Dalla Lana School of Public Health, U of T

The epidemiology and health system impact of mitochondrial disease and psychiatric conditions in Ontario: A population-based study.

Dr. Alessandro Colasanti, Senior Clinical Lecturer - Psychiatry; Brighton and Sussex Medical School

Neuropsychiatric and Brain Imaging Phenotyping of primary Mitochondrial Diseases

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Break.

Industry Speaker - Dr. Herma Renkema,

Chief Early Development Officer Khondrion

 

“Path From Research to Clinical Trials for Lead Compound Sonlicromanol (KH176)"

Closing Remarks for Day One.

- MitoFutures Trainee Development and Networking Hour -

Inviting all undergraduates, graduate students, postdoctoral fellows and PI's to learn how to apply AI to your own research and explore future opportunities in the field.

 

Guest Speaker: David Dai, Senior Data Scientist, St. Michael’s Hospital as part of Unity Health, Temerty Centre for AI Research and Education in Medicine

Note:  The MitoFurtures Trainee Development and Networking Hour requires a separate registration from the symposium.

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Friday April 9th

Welcome & Introduction of Fellows and Thomas Zachos Scholars with:

 

Blaine Penny (Member of the Board Director & Co-Founder Mitocanada Foundation)

 

and

Thomas Zachos (Patient Advocate & MITO2i Supporter).

Quick fire talks from the mitoFUTURES Fellows and Scholars, with Moderator Dr. Ruth Slack Professor University of Ottawa.

Jessika Royea - Departments of Biochemistry, Cellular and Molecular Medicine, Microbiology & Immunology University of Ottawa

Sigma-1 receptors as therapeutic targets for mitochondrial
dysfunction

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Minesh Kapadia​ - Department of Surgery Toronto Western Hospital, UHN, University of Toronto

Regulation of PINK1-Parkin Mitophagy by Molecular Chaperones

Mohamed Ariff Iqbal - Department of Cellular and Molecular Medicine
University of Ottawa

 

The importance of mitochondrial dynamics in maintenance of neural stem cell function

Aleksandra Marakhovskaia - Department of Pharmacology & Toxicology
University of Toronto
 

Establishing a novel role of mental illnesses associated gene, Fxr1in regulation of mitochondrial function in cortical neurons. Potential relevance for the mitochondrial function dysregulation in psychiatric disorders.

Aadil Ali - Toronto General Hospital, UHN, University of Toronto
 

Manipulation of Organ temperature and Metabolism for the
Extension of Donor Lung Preservation Times

Sanna Masud - Department of Molecular Genetics University of Toronto

Mapping the genetic interactions of TAZ: towards a functional wiring diagram of the mitochondrion

David Bodenstein - Department of Pharmacology & Toxicology University of Toronto

Novel approaches to eliminate mutant mitochondrial DNA and transplantation in patient-derived induced-pluripotent stem cells

Swathi Jeedigunta - Department of Molecular Genetics University of Toronto

Determining the role of PolG1 in eliminating deleterious mitochondrial DNA from the female germline

Panel Session: Mitochondria Highlights: Ophthalmology:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Dr. Ana Andreazza

Moderator - Scientific Director of  MITO2i

Dr. Rustum Karanjia
 

Assistant Professor and Vie-Chair Research, Department of Ophthalmology University of Ottawa

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Dr. Valerie Wallace

Professor Department of Ophthalmology & Vision Sciences

University Health Network (UHN)

Dr. Molly Shoichet 
 

University Professor Canada Research Chair in Tissue Engineering Department of Applied Chemistry and Chemical Engineering U of T.

Break.

Mitochondria Highlights: Organ Biology

Dr. Jason Maynes -

Chief, Anesthesia and Pain Medicine, Curtis Joseph and Harold Groves Chair in Anesthesia and Pain Medicine, Department of Anesthesia and Pain Medicine, Hospital for Sick Children

Dr. Isabella Cannigia -
Assistant Professor, Department of Physiology University of Toronto Investigator, LTRI, Mount Sinai
 

Announcement MITO2i and Toronto Dementia Research Alliance (TDRA) Partnership.

Dr. Reinhart Reithmeier

 

Vice Dean Research & Innovation

Temetry Faculty of Medicine U of T

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Dr. Tarek Rajji

 

Executive Director

Toronto Dementia Research Alliance

MITO2i Trainee Science Communication Session

MITO2i Trainee 60 – 90 second Videos

Remarks by Dr. Reinhart Reithmeier

Final Thank-you and Closing – MITO2i Team.